gastroenteritis - Blastocystis

Advices

1 months - 18 years
Priority	Medication	Remarks
Priority: 1st choice	Medication:	Remarks: SWAB remarks Niet behandelen tenzij langdurig onverklaarbare darmklachten.
Priority: 2nd choice	Medication: cotrimoxazol (trimethoprim + sulfamethoxazol) 7 days	Remarks: SWAB remarks Dosis cotrimoxazol: https://www.kinderformularium.nl/geneesmiddel/314/cotrimoxazol-sulfamethoxazol-trimethoprim
Priority: 2nd choice alternative	Medication: metronidazol 10 days	Remarks: SWAB remarks Dosis metronidazol: https://www.kinderformularium.nl/geneesmiddel/100/metronidazol.
Priority: 3rd choice	Medication: paromomycine 7 days	Remarks: SWAB remarks Dosis paromomycine: https://www.kinderformularium.nl/geneesmiddel/25/paromomycine

Pathogeniciteit van deze darmprotozoa is zeer omstreden, behandeling is dus in principe niet geindiceerd.

Paromomycine is in Nederland niet geregistreerd. Apotheken kunnen het middel met een artsenverklaring bestellen.

Pubmed.gov publication # 23961439
Sekar U and Shanthi M (2013) Blastocystis: consensus of treatment and controversies. Trop Parasitol. 3: 35–39.
Pubmed.gov publication # 23053509
van Hellemond JJ, Molhoek N, Koelewijn R, Wismans PJ, van Genderen PJJ (2013) Is paromomycin the drug of choice for eradication of Blastocystis in adults? J Infect Chemother. 2013 Jun;19(3):545-8
Pubmed.gov publication # 19834337
Stensvold CR, et al. (2010) Eradication of Blastocystis carriage with antimicrobials: reality or delusion? J Clin Gastroenterol. 44: 85-90
http://www.mimg.ucla.edu/faculty/campbell/drugs_for_parasites.pdf
CDC (2004) Drugs for parasitic infections. The Medical Letter 46, 1-12
SWAB Guideline IX - Acute infectieuze diarree

View all guidelines
Pubmed.gov publication # 12650658
Nigro L. et al. 2003. A placebo-controlled treatment trial of Blastocystis hominis infection with metronidazole. J Travel Med. 10:128-30.

The following antimicrobial agents have been used in these recommendations:

Swab vid: G-272205.3
Updated: 06/14/2019 - 10:59
Status: Published